I think a Penn State has two weaknesses right now. Their field goal kicking has been way off, making only about 50% so far. And their offensive line is still a work in process, allowing blitzing teams to pressure McSorely or stop Barkley from running effectively. Indiana was effective at this, but Barkley, a likely Heisman Trophy winner, will still get his yards, either through kickoff returns as he showed against a Indiana, or as a receiver out of the backfield. One other possible weakness is the health of their star tight end, Gesecki, who may be held out leading up to the bye week in order to be healthy for the Michigan and OSU games which follow.
I won't talk about their strengths unless asked, and btw my father in law was a Northwestern business school alum, so I married into your family (and vice versa). I'm a Penn State fan and I think we will win the game, but I believe it will be close. All Big10 road games are tough, and playing at 11:00 AM in your venue is ....different. Anyway, I'm not here to troll - good luck and I hope for a well fought injury free game.